NeuroGen Brain and Spine Institute is not just an organization, but a collective, committed concept, of paving the way to a brighter future, and a life of independence, for individuals with incurable neurological disorders, through the combination of revolutionary regenerative medicine, holistic comprehensive neurorehabilitation and medical intervention.
In the past donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: The stem cells do not have tissue-specific structures to perform specialized functions.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read extra details on NeuroGen Hospital.
Occupational therapists evaluate a child’s needs by testing his or her fine motor skills, perception and oral motor skills. By observing how the child responds to touch and movements, the therapist can determine a treatment plan. The treatment plan typically involves positioning, reaching, grasping and releasing. These skills are important for a child to develop the ability to be independent. Occupational therapy for children usually involves a form of play to keep them motivated. Many children with cerebral palsy have sensory impairments that make movement difficult. Our senses help us recognize changes in temperature, feel pain and to be aware of the space around us. Senses, such as touch and balance, are important for motor skills like picking up objects and walking.
A few advices to help your child with autism: Be consistent. Children with ASD have a hard time applying what they’ve learned in one setting (such as the therapist’s office or school) to others, including the home. For example, your child may use sign language at school to communicate, but never think to do so at home. Creating consistency in your child’s environment is the best way to reinforce learning. Find out what your child’s therapists are doing and continue their techniques at home. Explore the possibility of having therapy take place in more than one place in order to encourage your child to transfer what he or she has learned from one environment to another. It’s also important to be consistent in the way you interact with your child and deal with challenging behaviors. Look for nonverbal cues. If you are observant and aware, you can learn to pick up on the nonverbal cues that children with ASD use to communicate. Pay attention to the kinds of sounds they make, their facial expressions, and the gestures they use when they’re tired, hungry, or want something.
A spinal cord injury is damage to the spinal cord. It’s an extremely serious type of physical trauma that’s likely to have a lasting and significant impact on most aspects of daily life. The spinal cord is a bundle of nerves and other tissue that the vertebrae of the spine contains and protects. The vertebrae are the bones stacked on top of each other that make up the spine. The spine contains many nerves, and extends from the brain’s base down the back, ending close to the buttocks.
Did you know that stem cells, unlike other cells in the body, continue to divide for long periods of time and can help strengthen the immune system, effectively fighting infections and pathogens from the external environment. In addition, stem cells in the placenta and umbilical cord are important sources of platelets and red cells, which carry oxygen and nutrients to the blood. Stem cell harvesting can be done regardless of the time of birth: vaginal birth, caesarean section, multiple birth, premature birth or water birth.
Prolonged inactivity of limbs, may result in severe spasticity leading to permanent deformities. These may eventually need surgical correction. These symptoms may arise especially at the joints resulting in bent wrist, closed fist, flexed elbow. These may or may not straighten when forcefully tried. Poor feeding could result in malnourishment, which leads to a poor immunity, and low body weight. Poor neck control leads to swallowing difficulties in children with cerebral palsy. Often, the food taken orally may enter the larynx and trachea(windpipe), instead of the pharynx and oesophagus(food pipe). This could also be a common cause of recurrent pneumonia and other respiratory infections in cerebral palsy kids. Such cases of cerebral palsy could need eventual ventilatory support. Read more info Cerebral Palsy Treatment.