NeuroGen’s unwavering distinctiveness lies in its ability to combine seamlessly, the newest developments (stem cells) with conventional, tried and tested rehabilitation techniques. The amalgamation of the new and the old in the form of synergistic teamwork, all under one roof, enables our patients to hope, in an otherwise despondent condition, for the possibility of a better quality of life.
Some time ago donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: They can divide and replicate themselves as long as the person is alive.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. See extra info on NeuroGen Hospital.
Speech therapy also tackles problems that affect a child’s ability to eat. Many children with CP struggle to maintain a healthy weight because it’s hard to chew or swallow food. Oral motor exercises can improve the ability to chew and swallow food effectively. Speech therapists also work with other therapists. For example, a speech therapist and an occupational therapist can help children with drooling problems due to low muscle tone in the face and mouth. There are multiple surgical treatments that can help correct movement problems in children with cerebral palsy. However, parents should keep in mind that surgery isn’t right for every child with cerebral palsy. Surgery is most commonly prescribed for those with spastic cerebral palsy because their increased muscle tone can be reduced to relieve restricted movement. For example, a child who walks on their toes due to high muscle tone in their legs can have those muscles or tendons lengthened, allowing for more normal walking.
A few advices to help your child with autism: Pay attention to your child’s sensory sensitivities. Many children with ASD are hypersensitive to light, sound, touch, taste, and smell. Some children with autism are “under-sensitive” to sensory stimuli. Figure out what sights, sounds, smells, movements, and tactile sensations trigger your kid’s “bad” or disruptive behaviors and what elicits a positive response. What does your child find stressful? Calming? Uncomfortable? Enjoyable? If you understand what affects your child, you’ll be better at troubleshooting problems, preventing situations that cause difficulties, and creating successful experiences.
Try to “decode” your child’s messages and communicate with him in an intelligible way. Without prejudice, learn that the things that are simple to you, come step by step for people with autism. If you enter their world, they will feel unconditional love, they will feel safe and will flourish more easily. Do things for yourself, your family and your world! Learn to look at autism as a developing thing, not as an intended thing. This vision can provide you with strategies to deal with the challenges. The challenges that a child with autism can face can give you a strong impetus to support the whole family, the future of the child and the whole environment.
US researchers are now trying to find a way to use stem cells for patients with paralysis or brain injury, for patients with type 1 diabetes, those with spinal cord injury, heart disease, people who have a heart attack or disorder neurological disorders such as multiple sclerosis. Many of the studies have been carried out on animals, and the results are in an early stage. It is important to note that the treatment with stem cells is not done with the patient’s own stem cells, because this is how the premises of the disease return are created. However, there were exceptions, proof stands a case from 2007, published in the journal Pediatric, of a child who was ill with leukemia and who was transplanted his own stem cells harvested at birth, following that 5 years after the intervention, the child to be completely healthy. Instead, it is indicated that the stem cell donors are the patient’s brother or sister. But in only 25% of cases it is shown that the brother is compatible with the patient, and 7 out of 10 patients must seek a donor outside the family.
Stem cell therapy is the finest medical breakthrough in history. It has bagged the much acclaimed ‘Nobel Prize in Medicine’ in the year 2012. This miracle discovery, Stem Cell therapy, has leveraged and firmly positioned India in the field of medical science, worldwide. Stem cell therapy has changed the medical perception of ‘incurable neurological disorders’ and has broken all shackles. Regenerative medicine or stem cell therapy is one of the most promising branches of advanced medication. Its main objective is to restore organ and tissue function for patients with continual and persistent diseases. Over the years, scientists and surgeons have been using stem cell therapy to renew and repair tissues affected with age, disease and congenital defects. Read extra info at Stem Cell Therapy.